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TAF3 Antibody

  • 中文名稱：
    TAF3兔多克隆抗體
  • 貨號：
    CSB-PA564583
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from K562 cells, using TAF3 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TAF3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TAF3
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human TAF3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
  • 基因功能參考文獻：
    1. Data show that transcription cofactor TAF3 is required for transcription of the alpha spectrin SPTA1 gene. PMID: 23935956
    2. Study shows that H3K4me3-TAF3 interactions direct global TFIID recruitment to active genes, some of which are p53 targets. Further analyses show that H3K4me3 enhances p53-dependent transcription by stimulating preinitiation complex formation. PMID: 23452851
    3. Study shows that this TAF3 activity is critical for early lineage segregation during stem cell differentiation. PMID: 21884934
    4. Data identified TAF3 as an evolutionarily conserved negative regulator of p53 transcription activation function. PMID: 18549481
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TAF3 family
  • 數據庫鏈接：

    HGNC: 17303

    OMIM: 606576

    KEGG: hsa:83860

    STRING: 9606.ENSP00000340271

    UniGene: Hs.527688



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