国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SMIM1 Antibody, Biotin conjugated

SMIM1 Antibody, Biotin conjugated

  • 中文名稱：
    SMIM1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA450720LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SMIM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SMIM1
  • 別名：
    Small integral membrane protein 1 antibody; SMIM1 antibody; SMIM1_HUMAN antibody; Vel blood group antigen antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Small integral membrane protein 1 protein (1-46AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Regulator of red blood cell formation.
  • 基因功能參考文獻：
    1. rs1175550G and to a lesser extent rs143702418C independently increase SMIM1 and Vel antigen expression. PMID: 28084402
    2. Among the 448 samples analysed, 10 (2.23%) harboured the 17 bp deletion of the gene SMIM1, and all were heterozygote for the SMIM1*64_80 del allele. PMID: 27328373
    3. Alleles that initially entered the population have been maintained within the population. The c.64_80del null allele of SMIM1 is one such allele, thus having implications for transfusion medicine and child or maternal health. PMID: 26666208
    4. SMIM1 carries the Vel antigen as a type II membrane protein with a predicted C-terminal extracellular domain of only 3-12 amino acids PMID: 26452714
    5. Weak Vel expression levels are caused by multiple genetic factors in SMIM1 and probably also by other genetic or environmental factors. PMID: 25647324
    6. A cohort of 70 Vel- individuals was found to be uniformly homozygous for a 17 nucleotide deletion in the coding sequence of SMIM1. PMID: 23505126
    7. Loss of SMIM1 is associated with reduction in red blood cell formation. PMID: 23563606
    8. Loss of SMIM1 is associated with reduction in red blood cell formation. PMID: 23563608

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    SMIM1 family
  • 組織特異性：
    Highly expressed in the bone marrow and expressed at lower levels in non-hematopoietic tissues. Highly expressed in erythroleukemia cell lines. Up-regulated in CD34+ hematopoietic progenitors cultured toward red blood cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 44204

    OMIM: 615242

    KEGG: hsa:388588

    STRING: 9606.ENSP00000457386

    UniGene: Hs.22047



主站蜘蛛池模板： 夏河县| 江津市| 岳西县| 林芝县| 灵石县| 云林县| 新和县| 荆州市| 株洲市| 米易县| 曲靖市| 平利县| 崇左市| 化州市| 新疆| 新野县| 海门市| 葫芦岛市| 盐津县| 揭西县| 资阳市| 扎兰屯市| 营口市| 仙桃市| 衡阳市| 澜沧| 且末县| 化州市| 体育| 汉沽区| 琼海市| 遂昌县| 昭通市| 孟村| 福鼎市| 右玉县| 江口县| 儋州市| 富锦市| 平顶山市| 当涂县|