SH3GL3 Antibody

說(shuō)明書

產(chǎn)品詳情

Uniprot No.：

Q99963
基因名：

SH3GL3
別名：

CNSA3 antibody; EEN 2B L3 antibody; EEN B2 antibody; EEN-B2 antibody; EEN2BL3 antibody; EENB2 antibody; Endophilin 3 antibody; Endophilin A3 antibody; Endophilin-3 antibody; Endophilin-A3 antibody; H.sapiens mRNA for protein containing SH3 domain, SH3GL3 antibody; HsT19371 antibody; SH3 domain containing GRB2 like protein 3 antibody; SH3 domain GRB2 like 3 antibody; SH3 domain protein 2C antibody; SH3 domain-containing GRB2-like protein 3 antibody; SH3D2C antibody; SH3G3_HUMAN antibody; SH3GL3 antibody; SH3P13 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human SH3GL3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
基因功能參考文獻(xiàn)：
1. Our findings indicate that SH3GL3 plays an important role in myeloma cell migration/invasion, stemness and chemo-resistance. The SH3GL3-mediated myeloma cell migration/invasion is mediated by FAK/PI3K signaling pathway. PMID: 27683032
2. Aberrant DNA methylation of SH3GL3 gene is associated with colorectal cancer. PMID: 22901147
3. SH3GL3 as a novel glioma invasion-associated candidate gene that likely contribute to the invasive phenotype of malignant gliomas. PMID: 21722156
4. These data implicate ataxin-2 to play a role in endocytic receptor cycling.[Endophilin A3] PMID: 18602463
5. importance of hapln1b and sh3gl3 in embryonic vascular development PMID: 19308258
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亞細(xì)胞定位：

Cytoplasm. Early endosome membrane; Peripheral membrane protein.
蛋白家族：

Endophilin family
組織特異性：

Brain and testis.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 10832

OMIM: 603362

KEGG: hsa:6457

STRING: 9606.ENSP00000391372

UniGene: Hs.270055

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