国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SCUBE3 Antibody

SCUBE3 Antibody

  • 中文名稱：
    SCUBE3兔多克隆抗體
  • 貨號：
    CSB-PA020868GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SCUBE3
  • 別名：
    CEGF3 antibody; CUB and EGF containing protein 3 antibody; CUB and EGF-like domain-containing protein 3 antibody; CUB domain and EGF like repeat containing 3 antibody; DKFZp686B09105 antibody; DKFZp686B1223 antibody; DKFZp686D20108 antibody; FLJ34743 antibody; OTTHUMP00000016250 antibody; SCUB3_HUMAN antibody; SCUBE 3 antibody; SCUBE3 antibody; Signal peptide antibody; Signal peptide CUB and EGF like domain containing protein 3 antibody; Signal peptide CUB domain EGF like 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SCUBE3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
  • 基因功能參考文獻：
    1. The results of this pioneering study indicate that SCUBE protein family appears to have a probable role in the pathogenesis and angiogenesis development in psoriasis and SCUBE 1 and 3 may be novel markers of angiogenesis in psoriasis. PMID: 28238185
    2. Elevated expression of SCUBE3 in osteosarcoma tissues correlated with poor prognosis of the osteosarcoma patients. PMID: 27259322
    3. Results indicated that SCUBE3 might be involved in regulating the epithelial-mesenchymal transition (EMT) and malignant progression in NSCLC. PMID: 24390364
    4. Scube3 facilitates both TGFbeta and Hh signalling within an overall role of facillating inflammatory angiogenesis. PMID: 24084593
    5. results show that SCUBE3 knockdown was associated with lower vascular permeability in the tumor and effectively inhibited the metastatic potential of non-small-cell lung carcinoma PMID: 23420440
    6. in lung cancer cells, SCUBE3 could serve as an endogenous autocrine and paracrine ligand of TGF-beta type II receptor, which could regulate TGF-beta receptor signaling and modulate EMT and cancer progression PMID: 21441952
    7. Observational study of gene-disease association. (HuGE Navigator) PMID: 20546612
    8. may act locally and/or distantly through a proteolytic mechanism, and may play an important role in bone cell biology PMID: 15234972

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Cell surface.
  • 組織特異性：
    Highly expressed in osteoblasts. In normal lung, mainly expressed in bronchial epithelial cells. Tends to be up-regulated in lung cancer cells.
  • 數據庫鏈接：

    HGNC: 13655

    OMIM: 614708

    KEGG: hsa:222663

    STRING: 9606.ENSP00000274938

    UniGene: Hs.12923



主站蜘蛛池模板： 南华县| 鹤山市| 克什克腾旗| 邮箱| 即墨市| 高安市| 贵定县| 且末县| 枞阳县| 汝南县| 沾化县| 长岛县| 日喀则市| 黑水县| 五莲县| 德安县| 农安县| 龙门县| 农安县| 金昌市| 黑山县| 桑植县| 衡南县| 博罗县| 彝良县| 通海县| 霍城县| 浠水县| 平顶山市| 酉阳| 本溪市| 贵南县| 报价| 灵宝市| 怀柔区| 瓮安县| 抚宁县| 南康市| 绩溪县| 耒阳市| 资兴市|