SBNO2 Antibody, Biotin conjugated

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SBNO2 Polyclonal antibody
Uniprot No.：

Q9Y2G9
基因名：

SBNO2
別名：

SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.
基因功能參考文獻：
1. The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162
蛋白家族：

SBNO family
組織特異性：

Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.
數據庫鏈接：

HGNC: 29158

OMIM: 615729

KEGG: hsa:22904

STRING: 9606.ENSP00000354733

UniGene: Hs.408708