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RIC1 Antibody, Biotin conjugated

  • 中文名稱：
    RIC1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA671121LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RIC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RIC1
  • 別名：
    Connexin-43-interacting protein of 150 kDa antibody; Kiaa1432 antibody; Protein RIC1 homolog antibody; RIC1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.
  • 基因功能參考文獻：
    1. KIAA1432 is a novel gene activated by amplification in Small Cell Lung Cancers. PMID: 23716474
    2. These results suggest that the newly identified domain is essential for the proper phosphorylation and localization of Cx43, and CIP150 is a novel partner protein targeting this domain. PMID: 16112082
  • 亞細胞定位：
    Cytoplasm, cytosol. Membrane.
  • 蛋白家族：
    RIC1 family
  • 組織特異性：
    Present in kidney and various cell lines (at protein level). Widely expressed at low level.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17686

    OMIM: 610354

    KEGG: hsa:57589

    STRING: 9606.ENSP00000416696

    UniGene: Hs.211520



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