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中文名稱:
RGS22兔多克隆抗體
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貨號:
CSB-PA276672
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規格:
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圖片:
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA276672(RGS22 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA276672(RGS22 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
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其他:
產品詳情
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Uniprot No.:
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基因名:
RGS22
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別名:
FLJ40080 antibody; FLJ75004 antibody; MGC102908 antibody; PRTD-NY2 antibody; Regulator of G-protein signaling 22 antibody; RGS22 antibody; RGS22_HUMAN antibody
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宿主:
Rabbit
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反應種屬:
Human
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免疫原:
Fusion protein of Human RGS22
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免疫原種屬:
Homo sapiens (Human)
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標記方式:
Non-conjugated
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抗體亞型:
IgG
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純化方式:
Antigen affinity purification
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濃度:
It differs from different batches. Please contact us to confirm it.
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保存緩沖液:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式:
Liquid
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應用范圍:
ELISA,IHC
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推薦稀釋比:
| Application |
Recommended Dilution |
| ELISA |
1:2000-1:5000 |
| IHC |
1:25-1:100 |
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Protocols:
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儲存條件:
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
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基因功能參考文獻:
- Regulator of G-protein signaling 22 (RGS22) was identified as a direct target of miR-1260b and was inhibited by miR-1260b. Knockdown of RGS22 increased proliferation of hepatocellular carcinoma cells. PMID: 29038925
- New basal cell carcinoma susceptibility loci were identified at TGM3 (rs214782) and RGS22(rs7006527). PMID: 24403052
- Over-expression of RGS22 in a highly metastatic esophageal cancer cell line causes decrease in cell migration and reduction in the invasive potential of the cells. PMID: 21533872
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亞細胞定位:
Cytoplasm. Nucleus. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus.
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組織特異性:
Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).
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數據庫鏈接:
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