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中文名稱：
RGS12兔多克隆抗體
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貨號：
CSB-PA694009
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規格：
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圖片：
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其他：
產品詳情
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產品名稱：
Rabbit anti-Homo sapiens (Human) RGS12 Polyclonal antibody
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Uniprot No.：
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基因名：
RGS12
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Synthesized peptide derived from N-terminal of Human RGS12.
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免疫原種屬：
Homo sapiens (Human)
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克隆類型：
Polyclonal
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純化方式：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：
It differs from different batches. Please contact us to confirm it.
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產品提供形式：
Liquid
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應用范圍：
ELISA,WB
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推薦稀釋比：
| Application |
Recommended Dilution |
| WB |
1:500-1:3000 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.; Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.
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基因功能參考文獻：
- Findings identify RGS12 as a candidate tumor-suppressor gene in AA prostate cancer, which acts by decreasing expression of AKT and MNX1, establishing a novel oncogenic axis in this disparate disease setting. PMID: 28611045
- Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS12 in fine-tuning TRPC4 activities. PMID: 26987813
- RGS12 is essential for the terminal differentiation of osteoclasts induced by RANKL. PMID: 17042716
- shows chromosomal mapping information for human locus. PMID: 9168931
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亞細胞定位：
Nucleus. Cytoplasm. Cell projection, dendrite. Cell junction, synapse.; [Isoform 5]: Nucleus matrix.
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組織特異性：
Isoform 3 is brain specific.
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數據庫鏈接：
Most popular with customers
Western blot analysis of extracts from 3T3 cells, using RGS12 antibody.
