国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB11FIP4 Antibody

RAB11FIP4 Antibody

  • 中文名稱：
    RAB11FIP4兔多克隆抗體
  • 貨號：
    CSB-PA003902
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HT29 cells using Rab11-FIP4 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RAB11FIP4 antibody; ARFO2 antibody; KIAA1821 antibody; Rab11 family-interacting protein 4 antibody; FIP4-Rab11 antibody; Rab11-FIP4 antibody; Arfophilin-2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Rab11-FIP4.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
  • 基因功能參考文獻：
    1. Rab11-FIP4 expression promotes migration and invasion of colon cancer cells and correlates with poor prognosis. PMID: 29257314
    2. Our findings suggest that overexpression of Rab11-FIP4 predicts poor clinical outcomes for pancreatic cancer and contributes to pancreatic tumor progression. PMID: 28035375
    3. Results show the expression of Rab11-FIP4 upregulated in hepatocellular carcinoma (HCC) and correlated with poor prognosis. Rab11-FIP4 dramatically contributed to HCC metastasis via phosphorylation of PRAS40. PMID: 25745995
    4. Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells. PMID: 12470645
    5. FIP3 and FIP4 serve to couple Rab11-positive vesicle traffic from recycling endosomes to the cleavage furrow/midbody where they are tethered prior to fusion events via interactions with Arf6 and the Exocyst. PMID: 16148947

    顯示更多

    收起更多

  • 亞細胞定位：
    Endosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle.
  • 組織特異性：
    Present at high level in testis (at protein level). Weakly expressed in other tissues.
  • 數據庫鏈接：

    HGNC: 30267

    OMIM: 611999

    KEGG: hsa:84440

    STRING: 9606.ENSP00000312837

    UniGene: Hs.406788



主站蜘蛛池模板： 大悟县| 玉门市| 项城市| 射洪县| 永州市| 通道| 昌邑市| 满洲里市| 咸阳市| 朝阳区| 秦皇岛市| 都江堰市| 兴业县| 商都县| 高唐县| 赫章县| 临湘市| 奉化市| 库伦旗| 昌江| 邳州市| 望江县| 汤阴县| 南通市| 枣阳市| 青神县| 东方市| 长兴县| 汉沽区| 临潭县| 新蔡县| 三门峡市| 深水埗区| 吉木萨尔县| 英超| 仁寿县| 布尔津县| 黄浦区| 博兴县| 塔城市| 小金县|