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  4. PRICKLE3 Antibody

PRICKLE3 Antibody

  • 中文名稱(chēng)：
    PRICKLE3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA018678PA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, PC-3 whole cell lysate
      All lanes: PRICKLE3 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 69, 60 kDa
      Observed band size: 69 kDa
    • IHC image of CSB-PA018678PA01HU diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) PRICKLE3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PRICKLE3 antibody; LMO6Prickle planar cell polarity protein 3 antibody; LIM domain only protein 6 antibody; LMO-6 antibody; Prickle-like protein 3 antibody; Pk3 antibody; Triple LIM domain protein 6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Peptide sequence from Human Prickle-like protein 3 protein (9-24AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，PRICKLE3 Antibody (CSB-PA018678PA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于PRICKLE3 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA018678PB01HU PRICKLE3 Antibody, HRP conjugated ELISA
    FITC CSB-PA018678PC01HU PRICKLE3 Antibody, FITC conjugated
    Biotin CSB-PA018678PD01HU PRICKLE3 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation. PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module. Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions. Involved in the organization of the basal body. Involved in cilia growth and positioning. Required for proper assembly, stability, and function of mitochondrial membrane ATP synthase (mitochondrial complex V).
  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion.
  • 蛋白家族：
    Prickle / espinas / testin family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 6645

    OMIM: 300111

    KEGG: hsa:4007

    STRING: 9606.ENSP00000365494

    UniGene: Hs.732712



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