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PAM16 Antibody

  • 中文名稱：
    PAM16兔多克隆抗體
  • 貨號：
    CSB-PA896711DA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: PAM16 antibody at 2μg/ml
      Lane 1: HL60 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 14 kDa
      Observed band size: 14 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PAM16 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PAM16
  • 別名：
    CGI-136 antibody; MAGMAS antibody; Magmas like protein antibody; Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction antibody; Mitochondria-associated granulocyte macrophage CSF-signaling molecule antibody; Mitochondrial import inner membrane translocase subunit TIM16 antibody; PAM16 antibody; Presequence translocase-associated motor 16 homolog (S. cerevisiae) antibody; Presequence translocated-associated motor subunit PAM16 antibody; TIM16 antibody; TIM16_HUMAN antibody; TIMM16 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial import inner membrane translocase subunit TIM16 protein (1-125AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PAM16 Antibody (CSB-PA896711DA01HU)，的標記方式是Non-conjugated。對于PAM16 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA896711DB01HU PAM16 Antibody, HRP conjugated ELISA
    FITC CSB-PA896711DC01HU PAM16 Antibody, FITC conjugated
    Biotin CSB-PA896711DD01HU PAM16 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity.
  • 基因功能參考文獻：
    1. A novel essential role of Magmas is a 'ROS regulatory protein' in the maintenance of cellular redox homeostasis and imparting cytoprotection under oxidative stress. PMID: 25165880
    2. finding of deleterious MAGMAS mutations in an early lethal skeletal dysplasia supports a key role for this mitochondrial protein in the ossification process PMID: 24786642
    3. Magmas protects pituitary cells from apoptosis, suggesting its possible involvement in neoplastic transformation. PMID: 20719856
    4. Magmas expression in prostate cancer. PMID: 15704001
  • 相關疾病：
    Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type (SMDMDM)
  • 亞細胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    TIM16/PAM16 family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 29679

    OMIM: 613320

    KEGG: hsa:51025

    STRING: 9606.ENSP00000315693

    UniGene: Hs.730693



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