Western blot
All lanes: OCIAD1 antibody at 1μg/ml
Lane 1: Mouse liver tissue
Lane 2: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 21, 22 kDa
Observed band size: 28 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA882129LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA882129LA01HU at dilution of 1:100
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
基因功能參考文獻:
Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors. PMID: 22726067
OCIAD1 is a potential biomarker of thyroid carcinoma but had no significant additive effect on the risk of distant metastasis. PMID: 22081784
This is the first study to indicate that OCIAD1 is a key player in generating ovarian cancer recurrence. PMID: 20515946
Over-expressed in metastatic ovarian cancer. Effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Possibility of OCIAD1's role in tumor metastasis. PMID: 18328549
亞細胞定位:
Endosome.
蛋白家族:
OCIAD1 family
組織特異性:
Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.