NUDT2 Antibody
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中文名稱：NUDT2兔多克隆抗體
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貨號：CSB-PA2105ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA2105ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA2105ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) NUDT2 Polyclonal antibody
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Uniprot No.：
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基因名：NUDT2
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別名：2310051L06Rik antibody; 5''''-P1 antibody; AA939917 antibody; Ap4A hydrolase 1 antibody; Ap4A hydrolase antibody; AP4A_HUMAN antibody; Ap4Aase antibody; APAH 1 antibody; APAH1 antibody; Bis(5' nucleosyl) tetraphosphatase [asymmetrical] antibody; Bis(5''-nucleosyl)-tetraphosphatase [asymmetrical] antibody; Diadenosine 5'' antibody; Diadenosine 5',5''' P1,P4 tetraphosphate asymmetrical hydrolase antibody; Diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase antibody; Diadenosine tetraphosphatase antibody; EC 3.6.1.17 antibody; MGC10404 antibody; Nucleoside diphosphate linked moiety X motif 2 antibody; Nucleoside diphosphate-linked moiety X motif 2 antibody; nudix (nucleoside diphosphate linked moiety X)-type motif 2 antibody; Nudix motif 2 antibody; Nudix-type motif 2 antibody; NUDT 2 antibody; NUDT2 antibody; OTTHUMP00000021256 antibody; OTTHUMP00000021257 antibody; OTTHUMP00000021258 antibody; OTTHUMP00000021259 antibody; P4-tetraphosphate asymmetrical hydrolase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Bis(5\'-nucleosyl)-tetraphosphatase [asymmetrical] protein (1-147AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP. Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro.
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基因功能參考文獻：
- NUDT2 is a novel complex formation enhancing factor regulating mTORC1-Rag GTPase signaling that is crucial for cell growth control. PMID: 28089905
- Regulation of gene expression is one of several roles proposed for the stress-induced nucleotide diadenosine tetraphosphate (Ap4A). We have examined this directly by a comparative RNA-Seq analysis of KBM-7 chronic myelogenous leukemia cells and KBM-7 cells in which the NUDT2 Ap4A hydrolase gene had been disrupted (NuKO cells), causing a 175-fold increase in intracellular Ap4A. PMID: 27144453
- This paper presents the crystal structure of wild-type and E58A mutant human Ap4A hydrolase. PMID: 23384440
- High NUDT2 is associated with breast carcinoma. PMID: 20533549
- In this study the authors present data demonstrating that the SARS-CoV 7a protein interacts with human Ap4A-hydrolase (asymmetrical diadenosine tetraphosphate hydrolase, EC 3.6.1.17). PMID: 20144233
- crystallographic structure and substrate-binding mechanism of Ap4A hydrolase PMID: 15596429
- NMR resonance assignments PMID: 15772762
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蛋白家族：Nudix hydrolase family
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數據庫鏈接：
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