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NP Antibody, HRP conjugated

Rare Species
  • 中文名稱：
    NP兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA841983HB01RCI
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Reston ebolavirus NP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NP
  • 別名：
    NP antibody; Nucleoprotein antibody; Nucleocapsid protein antibody; Protein N antibody; Reston NP antibody; rNP antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Reston ebolavirus
  • 免疫原：
    Recombinant Reston ebolavirus Nucleoprotein protein (414-739AA)
  • 免疫原種屬：
    Reston ebolavirus
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm. Each NP binds to six nucleotides of viral genomic RNA, three being exposed to the solvant and three hidden into the nucleocapsid. Recruits also host PPP2R5C phosphatase to dephosphorylate VP30 and thereby promote viral transcription. Upon virion assembly and budding, NP binds to VP24 and possibly host STAU1.
  • 亞細(xì)胞定位：
    Virion. Host cytoplasm.
  • 蛋白家族：
    Filoviruses nucleoprotein family