NOP2 Antibody

產品詳情

Uniprot No.：

P46087
基因名：

NOP2
別名：

NOP2 antibody; NOL1 antibody; NSUN1Probable 28S rRNA antibody; cytosine(4447)-C(5))-methyltransferase antibody; EC 2.1.1.- antibody; Nucleolar protein 1 antibody; Nucleolar protein 2 homolog antibody; Proliferating-cell nucleolar antigen p120 antibody; Proliferation-associated nucleolar protein p120 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human NOP2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in ribosomal large subunit assembly. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable).
基因功能參考文獻：
1. NOL1 represents a new route by which telomerase activates transcription of cyclin D1 gene, thus maintaining cell proliferation capacity PMID: 26906424
2. p120 has an rRNA:5-Methylcytosine-Methyltransferase activity. PMID: 26196125
3. Findings suggest a newly discovered role of Nop2 in both mature neurons and in cells possibly involved in the regeneration of nervous tissue PMID: 25481415
亞細胞定位：

Nucleus, nucleolus.
蛋白家族：

Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
數據庫鏈接：

HGNC: 7867

OMIM: 164031

KEGG: hsa:4839

STRING: 9606.ENSP00000382392

UniGene: Hs.534334