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  4. NMT2 Antibody

NMT2 Antibody

  • 中文名稱：
    NMT2兔多克隆抗體
  • 貨號：
    CSB-PA015901DSR1HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA015901DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA015901DSR1HU at dilution of 1:100
    • Immunoprecipitating NMT2 in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA015901DSR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
      Lane 2: CSB-PA015901DSR1HU (4μg) + HepG2 whole cell lysate (500μg)
      Lane 3: HepG2 whole cell lysate (20μg)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NMT2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EC 2.3.1.97 antibody; Glycylpeptide N tetradecanoyltransferase 2 antibody; Glycylpeptide N-tetradecanoyltransferase 2 antibody; Myristoyl CoA:protein N myristoyltransferase 2 antibody; Myristoyl-CoA:protein N-myristoyltransferase 2 antibody; N-myristoyltransferase 2 antibody; NMT 2 antibody; NMT2 antibody; NMT2_HUMAN antibody; Peptide N myristoyltransferase 2 antibody; Peptide N-myristoyltransferase 2 antibody; Type II N myristoyltransferase antibody; Type II N-myristoyltransferase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 protein (1-120AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
  • 基因功能參考文獻：
    1. ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA. PMID: 26621918
    2. induction of NMT2 may play a central role in dioxin carcinogenicity. PMID: 11731439
    3. NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID: 16123142
    4. Involved in progression and regulation of telomerase PMID: 16364039
    5. Protein-protein interaction of NMTs revealed that m-calpain interacts with NMT1 while caspase-3 interacts with NMT2. PMID: 16530191
    6. Disruption of the gene for NMT2 by a t(8;10) translocation in a male with hypogonadism. PMID: 17568424
    7. Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID: 18089753

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  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    NMT family
  • 數據庫鏈接：

    HGNC: 7858

    OMIM: 603801

    KEGG: hsa:9397

    STRING: 9606.ENSP00000367407

    UniGene: Hs.60339



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