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  4. NLGN4Y Antibody

NLGN4Y Antibody

  • 中文名稱：
    NLGN4Y兔多克隆抗體
  • 貨號：
    CSB-PA015858GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NLGN4Y
  • 別名：
    ASPGX2 antibody; AUTSX2 antibody; HGNC:14287 antibody; HLNX antibody; HNLX antibody; KIAA0951 antibody; KIAA1260 antibody; MGC22376 antibody; Neuroligin 4 X linked antibody; Neuroligin 4, Y linked antibody; Neuroligin X antibody; Neuroligin Y antibody; Neuroligin-4 antibody; NLGN antibody; NLGN4 antibody; NLGN4X antibody; NLGN4Y antibody; NLGNY_HUMAN antibody; Y-linked antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human NLGN4Y
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Putative neuronal cell surface protein involved in cell-cell-interactions.
  • 基因功能參考文獻：
    1. Results suggest an association between a maternal immune response to neuroligin 4 Y-linked (NLGN4Y) and subsequent sexual orientation in male offspring. PMID: 29229842
    2. Results suggest that NLGN4Y is an important negative regulator in prostate cancer progression. PMID: 27626693
    3. Expression of NLGN4Y, a gene that may be involved in synaptic function, is increased in boys with XYY PMID: 25558953
    4. investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism PMID: 19605777
    5. Neuroligin mutations most probably represent rare causes of autism; it is unlikely that the allelic variants in any of these genes would be major risk factors for autism. PMID: 16077734
    6. The coding sequences and splice junctions of the NLGN4Y gene were analyzed in 335 male samples (290 with autism and 45 with mental retardation) to analyze sequence variants in NLGN4Y that are associated with autism or mental retardation. PMID: 18628683

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  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.
  • 蛋白家族：
    Type-B carboxylesterase/lipase family
  • 組織特異性：
    Expressed in fetal and adult brain, prostate and testis.
  • 數據庫鏈接：

    HGNC: 15529

    OMIM: 400028

    KEGG: hsa:22829

    STRING: 9606.ENSP00000342535

    UniGene: Hs.439199