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NANS Antibody

  • 中文名稱：
    NANS兔多克隆抗體
  • 貨號：
    CSB-PA015440GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NANS
  • 別名：
    EC 2.5.1.56 antibody; EC 2.5.1.57 antibody; N acetylneuraminate 9 phosphate synthase antibody; N acetylneuraminate synthase antibody; N acetylneuraminic acid phosphate synthase antibody; N acetylneuraminic acid synthase antibody; N-acetylneuraminate synthase antibody; N-acetylneuraminate-9-phosphate synthase antibody; N-acetylneuraminic acid phosphate synthase antibody; N-acetylneuraminic acid synthase antibody; NANS antibody; OTTHUMP00000021769 antibody; SAS antibody; Sialic acid phosphate synthase antibody; Sialic acid synthase antibody; SIAS_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NANS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
  • 基因功能參考文獻：
    1. NANS deficiency is associated with defect in brain and skeletal development. PMID: 27213289
    2. sialic acid synthases kinetics and preliminary mutagenesis experiments reveal the importance of C-terminal antifreeze protein domain PMID: 16274664
    3. The structure of the C-terminal antifreeze-like domain of human sialic acid synthase was determined. The structure comprises one alpha- and two single-turn 3(10)-helices and two beta-strands, and is similar to those of the type III antifreeze proteins. PMID: 16597820
  • 相關疾病：
    Spondyloepimetaphyseal dysplasia, Genevieve type (SEMDG)
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 19237

    OMIM: 605202

    KEGG: hsa:54187

    STRING: 9606.ENSP00000210444

    UniGene: Hs.522310