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LRCH1 Antibody, HRP conjugated

  • 中文名稱：
    LRCH1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA897471LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LRCH1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LRCH1
  • 別名：
    LRCH1 antibody; CHDC1 antibody; KIAA1016 antibody; Leucine-rich repeat and calponin homology domain-containing protein 1 antibody; Calponin homology domain-containing protein 1 antibody; Neuronal protein 81 antibody; NP81 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
  • 基因功能參考文獻：
    1. In the analysis of hip osteoarthritis cases with superior maximum joint space narrowing (JSN) versus cases with non-superior maximum JSN we detected association with a variant in the LRCH1 gene. PMID: 27974301
    2. Letter: Did not observe an association between LRCH-1 SNPs and knee osteoarthritis. PMID: 22325041
    3. A genetic variant in LRCH1 was consistently associated with knee osteoarthritis in 3 samples from 2 populations. PMID: 16447229
    4. results suggest that there is no association between LRCH1 and knee osteoarthritis susceptibility PMID: 18049793
  • 亞細胞定位：
    Cytoplasm.
  • 數據庫鏈接：

    HGNC: 20309

    OMIM: 610368

    KEGG: hsa:23143

    STRING: 9606.ENSP00000374447

    UniGene: Hs.507971