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  4. KBTBD6 Antibody, HRP conjugated

KBTBD6 Antibody, HRP conjugated

  • 中文名稱：
    KBTBD6兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA774812LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KBTBD6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KBTBD6
  • 別名：
    KBTB6_HUMAN antibody; KBTBD6 antibody; Kelch repeat and BTB (POZ) domain containing 6 antibody; Kelch repeat and BTB domain-containing protein 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Kelch repeat and BTB domain-containing protein 6 protein (1-139AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation. By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes including the organization of the cytoskeleton, cell migration and cell proliferation. Ubiquitination of TIAM1 requires the membrane-associated protein GABARAP which may restrict locally the activity of the complex.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 數據庫鏈接：

    HGNC: 25340

    OMIM: 617738

    KEGG: hsa:89890

    STRING: 9606.ENSP00000368799

    UniGene: Hs.534040



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