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HMG20A Antibody

  • 中文名稱：
    HMG20A兔多克隆抗體
  • 貨號：
    CSB-PA010541GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    HMG20A
  • 別名：
    FLJ10739 antibody; High mobility group 20A antibody; High mobility group protein 20A antibody; HM20A_HUMAN antibody; HMG box containing protein 20A antibody; HMG box domain containing 1 antibody; HMG box-containing protein 20A antibody; HMG domain protein HMGX1 antibody; HMG domain-containing protein 1 antibody; HMG domain-containing protein HMGX1 antibody; hmg20a antibody; HMGX1 antibody; HMGXB1 antibody; Hypothetical protein FLJ10739 antibody; iBRAF antibody; Inhibitor of BRAF35 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human HMG20A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
  • 基因功能參考文獻：
    1. HMG20A together with LSD1 are required for SNAI1-dependent repression of epithelial genes. PMID: 25639869
    2. ectopic expression of BRAP2 inhibits nuclear localization of HMG20A and NuMA1, and prevents nuclear envelope accumulation of SYNE2. PMID: 23707952
    3. HMG20A/iBRAF forms heterodimers with HMG20B/BRAF35. Heterodimerization impairs HMG20B/BRAF35 sumoylation and interaction with the LSD1-CoREST complex. PMID: 22570500
    4. we report associations with the LAMA1 and HMG20A (not previously associated at genome-wide significance in Europeans) gene regions with type 2 diabetes risk PMID: 22693455
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 5001

    OMIM: 605534

    KEGG: hsa:10363

    STRING: 9606.ENSP00000336856

    UniGene: Hs.69594