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GRPEL1 Antibody

  • 中文名稱：
    GRPEL1兔多克隆抗體
  • 貨號：
    CSB-PA875707ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: GRPEL1 antibody at 1.37µg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 24 kDa
      Observed band size: 24 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA875707ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA875707ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GRPEL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ25609 antibody; GREPEL 1 antibody; GREPEL1 antibody; GrpE like 1 antibody; GrpE like 1 mitochondrial antibody; GrpE like protein cochaperone antibody; GrpE protein homolog 1 mitochondrial antibody; GrpE protein homolog 1; mitochondrial antibody; GRPE1_HUMAN antibody; GRPEL 1 antibody; Grpel1 antibody; HMGE antibody; Mt GrpE#1 antibody; Mt-GrpE#1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human GrpE protein homolog 1, mitochondrial protein (1-217AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
  • 基因功能參考文獻：
    1. Data suggest that two putative NEF (nucleotide exchange factors) orthologs, GRPEL1 and GRPEL2, modulate function of mitochondrial HSP70 (mtHSP70); both GRPEL1 and GRPEL2 associate with mtHSP70 as hetero-oligomeric subcomplex and regulate mtHSP70 transport. (GRPEL = mitochondrial GrpE-like protein; HSP70 = heat-shock protein 70) PMID: 28848044
    2. The low resolution structure of human GrpE presented suggests that GrpE is a symmetric dimer when not bound to DnaK PMID: 12840016
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    GrpE family
  • 數據庫鏈接：

    HGNC: 19696

    OMIM: 606173

    KEGG: hsa:80273

    STRING: 9606.ENSP00000264954

    UniGene: Hs.443723



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