GCFC2 Antibody

產品詳情

Uniprot No.：

P16383
基因名：

GCFC2
別名：

GCFC2 antibody; C2orf3 antibody; GCF antibody; TCF9GC-rich sequence DNA-binding factor 2 antibody; GC-rich sequence DNA-binding factor antibody; Transcription factor 9 antibody; TCF-9 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human TCF-9.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised introns.
基因功能參考文獻：
1. Authors propose the GCF regulated transcriptional activity, at least in part, contributed to the upregulation of IER5 on radiation in HepG2 cells. The present findings provide insights into understanding the regulatory mechanisms of IER5. PMID: 26915404
2. C2ORF3 protein is required for pre-mRNA splicing through its presumable role in efficient intron turnover PMID: 24304693
3. Study refined the 2p12 candidate region in two populations and report evidence supporting MRPL19 and C2ORF3 as candidate susceptibility genes for dyslexia. PMID: 17309879
亞細胞定位：

Nucleus, nucleoplasm. Nucleus, nucleolus.
蛋白家族：

GCF family
組織特異性：

Widely expressed in tissues and cell lines.
數據庫鏈接：

HGNC: 1317

OMIM: 189901

KEGG: hsa:6936

STRING: 9606.ENSP00000318690

UniGene: Hs.303808