G2E3 Antibody

中文名稱：

G2E3兔多克隆抗體
貨號：

CSB-PA741972LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of A549 cells with CSB-PA741972LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) G2E3 Polyclonal antibody
Uniprot No.：

Q7L622
基因名：

G2E3
別名：

G2E3 antibody; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase antibody; EC 2.3.2.26 antibody; G2/M phase-specific HECT-type E3 ubiquitin transferase antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase protein (240-337AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，G2E3 Antibody (CSB-PA741972LA01HU)，的標記方式是Non-conjugated。對于G2E3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA741972LB01HU	G2E3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA741972LC01HU	G2E3 Antibody, FITC conjugated
Biotin	CSB-PA741972LD01HU	G2E3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
基因功能參考文獻：
1. Results suggest that G2E3 is a molecular determinant of the DDR and cell survival. PMID: 25593194
2. Cell cycle phase-specific expression and highly regulated subcellular localization of G2E3 suggest a possible role in cell cycle regulation and the cellular response to DNA damage. PMID: 17239372
亞細胞定位：

Nucleus, nucleolus. Cytoplasm.
組織特異性：

Predominantly expressed in brain, liver, kidney, testes and ovary.
數據庫鏈接：

HGNC: 20338

OMIM: 611299

KEGG: hsa:55632

STRING: 9606.ENSP00000206595

UniGene: Hs.509008