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  4. FBXO8 Antibody

FBXO8 Antibody

  • 中文名稱：
    FBXO8兔多克隆抗體
  • 貨號：
    CSB-PA008517GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    FBXO8
  • 別名：
    DC10 antibody; F box only protein 8 antibody; F box protein 8 antibody; F box protein Fbx8 antibody; F box/SEC7 protein FBS antibody; F-box only protein 8 antibody; F-box/SEC7 protein FBS antibody; FBS antibody; FBX8 antibody; FBX8_HUMAN antibody; FBXO 8 antibody; Fbxo8 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human FBXO8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).
  • 基因功能參考文獻：
    1. Study demonstrates that down-regulation of FBX8 in hepatocellular carcinoma (HCC) correlates with poor survival of patients. All of the functional experiments confirm FBX8 as a tumor suppressor in the progression of HCC. The preferential down-regulation of FBX8 in HCC patients with invasion and metastasis suggested that FBX8 may be a significant biomarker for HCC progression. PMID: 23826080
    2. FBX8 as a metastasis suppressor that functions through mTOR signaling pathway and has significant prognostic power. PMID: 27916606
    3. FBX8 down-expression was an independent prognostic indicator for glioma patient's survival. PMID: 25550853
    4. FBX8 was markedly down-regulated in gastric cancer tissues. Knocking down FBX8 promoted proliferation and invasion in tumor cell line. Patients with low FBX8 had poor prognosis. PMID: 25801334
    5. FBX8 is a novel c-Myc binding protein and that c-Myc induces cell invasive activity PMID: 20848231

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  • 數(shù)據(jù)庫鏈接：

    HGNC: 13587

    OMIM: 605649

    KEGG: hsa:26269

    STRING: 9606.ENSP00000377280

    UniGene: Hs.76917