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FAM129A Antibody

  • 中文名稱：
    FAM129A兔多克隆抗體
  • 貨號：
    CSB-PA939303
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from A431 and DU145 cells using Niban Antibody.
    • Immunofluorescence staining of methanol-fixed Hela cells using Niban Antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FAM129A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FAM129A
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    peptide sequence around aa. 912~916 (K-E-G-E-G) derived from Human Niban.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:1000
    IF 1:100-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.
  • 基因功能參考文獻：
    1. Data suggest that decreasing C1orf24 protein levels by restoring microRNA miR-106b function may have therapeutic implications. PMID: 26317551
    2. DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
    3. Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
    4. The expression of Niban frequently begins in the early stages of head and neck squamous carcinoma and remains upregulated throughout the carcinogenic process. Niban may be a good molecular marker of HNSCC. PMID: 19536772
    5. Niban expression is up-regulated in various types of thyroid tumors. PMID: 16949643

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  • 亞細胞定位：
    Cytoplasm. Membrane; Lipid-anchor.
  • 蛋白家族：
    Niban family
  • 組織特異性：
    Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with
  • 數據庫鏈接：

    HGNC: 16784

    KEGG: hsa:116496

    STRING: 9606.ENSP00000356481

    UniGene: Hs.518662