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  4. EPGN Antibody

EPGN Antibody

  • 中文名稱：
    EPGN兔多克隆抗體
  • 貨號：
    CSB-PA036549
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Jurkat cells, 293T cells, hela cells, Primary antibody: CSB-PA036549(EPGN Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    EPGN
  • 別名：
    ALGV3072 antibody; EPG antibody; EPGN antibody; EPGN_HUMAN antibody; Epigen antibody; Epigen precursor antibody; Epithelial mitogen antibody; PRO9904 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human EPGN
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
  • 基因功能參考文獻：
    1. Study shows how the EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. Results reveal how responses to different EGFR ligands are defined by receptor dimerization strength and signaling dynamics. These findings have broad implications for understanding receptor tyrosine kinase (RTK) signaling specificity. PMID: 28988771
    2. cloning of a related gene in mouse PMID: 112783
    3. EPG is an EGF-like growth factor and a low affinity ligand PMID: 15611079
  • 亞細胞定位：
    [Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 2]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.
  • 數據庫鏈接：

    HGNC: 17470

    KEGG: hsa:255324

    UniGene: Hs.401237



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