CPLX3 Antibody

產品詳情

Uniprot No.：

Q8WVH0
基因名：

CPLX3
別名：

CPLX3 antibody; Nbla11589Complexin-3 antibody; Complexin III antibody; CPX III antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human CPLX3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release.
基因功能參考文獻：
1. CPX acts sequentially on assembling SNAREpins, first facilitating zippering by nearly doubling the distance at which v- and t-SNAREs can engage and then clamping them into a half-zippered fusion-incompetent state. PMID: 21785413
亞細胞定位：

Cell junction, synapse. Cell membrane; Lipid-anchor.
蛋白家族：

Complexin/synaphin family
數據庫鏈接：

HGNC: 27652

OMIM: 609585

KEGG: hsa:594855

STRING: 9606.ENSP00000378464

UniGene: Hs.187694