COPG2 Antibody

產(chǎn)品詳情

Uniprot No.：

Q9UBF2
基因名：

COPG2
別名：

2 COP antibody; Coat protein nonclathrin gamma 2 cop antibody; Coatomer protein complex subunit gamma 2 antibody; Coatomer subunit gamma 2 antibody; Coatomer subunit gamma-2 antibody; COPG 2 antibody; Copg2 antibody; COPG2_HUMAN antibody; DKFZp761N09121 antibody; FLJ11781 antibody; Gamma 2 coat protein antibody; Gamma 2 COP antibody; Gamma-2-coat protein antibody; Gamma-2-COP antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human COPG2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
基因功能參考文獻(xiàn)：
1. In cortices, the MEST promoter was hemimethylated, as expected for a differentially methylated imprinting control region, whereas the COPG2 and TSGA14 promoters were completely demethylated, typical for transcriptionally active non-imprinted genes. PMID: 22456293
2. Mutation sscreening and imprinting analysis of candidate genes for autism in the 7q32 region PMID: 11920156
亞細(xì)胞定位：

Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

COPG family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 2237

OMIM: 604355

KEGG: hsa:26958

STRING: 9606.ENSP00000393912

UniGene: Hs.6421