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COG4 Antibody

  • 中文名稱：
    COG4兔多克隆抗體
  • 貨號：
    CSB-PA881003ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA881003ESR1HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA881003ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) COG4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    COG4
  • 別名：
    COG4Conserved oligomeric Golgi complex subunit 4 antibody; COG complex subunit 4 antibody; Component of oligomeric Golgi complex 4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Conserved oligomeric Golgi complex subunit 4 protein (506-785AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
  • 基因功能參考文獻：
    1. A novel R729W missense mutation in COG4 was associated with the congenital disorder of glycosylation type II. PMID: 19494034
    2. The 1.9 A crystal structure of a Cog4 C-terminal fragment, was determined. Arg 729 is found to occupy a key position at the center of a salt bridge network, thereby stabilizing Cog4's small C-terminal domain. PMID: 19651599
  • 相關疾病：
    Congenital disorder of glycosylation 2J (CDG2J)
  • 亞細胞定位：
    Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    COG4 family
  • 數據庫鏈接：

    HGNC: 18620

    OMIM: 606976

    KEGG: hsa:25839

    STRING: 9606.ENSP00000315775

    UniGene: Hs.208680