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CMBL Antibody

產(chǎn)品詳情

Uniprot No.：

Q96DG6
基因名：

CMBL
別名：

Carboxymethylenebutenolidase homolog (Pseudomonas) antibody; Carboxymethylenebutenolidase homolog antibody; cmbl antibody; CMBL_HUMAN antibody; FLJ23617 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human CMBL
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
基因功能參考文獻(xiàn)：
1. By comparing the enzyme kinetics and chemical inhibition properties between the recombinant protein and tissue preparations, CMBL was shown to be the primary olmesartan medoxomil bioactivating enzyme in the liver and intestine. PMID: 20177059
亞細(xì)胞定位：

Cytoplasm, cytosol.
蛋白家族：

Dienelactone hydrolase family
組織特異性：

Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
數(shù)據(jù)庫鏈接：

HGNC: 25090

OMIM: 613379

KEGG: hsa:134147

STRING: 9606.ENSP00000296658

UniGene: Hs.192586