CHRAC1 Antibody

產品詳情

Uniprot No.：

Q9NRG0
基因名：

CHRAC1
別名：

CHARC1 antibody; CHARC15 antibody; CHRAC-1 antibody; CHRAC-15 antibody; Chrac1 antibody; CHRAC15 antibody; CHRC1_HUMAN antibody; Chromatin accessibility complex 1 antibody; Chromatin accessibility complex 15 kDa protein antibody; Chromatin accessibility complex protein 1 antibody; DNA polymerase epsilon subunit p15 antibody; histone-fold protein CHRAC15 antibody; HuCHRAC15 antibody; YCL1 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the C-terminal region of Human CHRAC15.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

IHC, ELISA

推薦稀釋比：

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:5000

Protocols：

Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex.
基因功能參考文獻：
1. -RAD21 and EIF3H, both on chromosome 8q23, CHRAC1 on chromosome 8q24.3 and TANC2 on chromosome 17q23-were confirmed to be driver genes regulating the proliferation/survival of clonogenic breast cancer cells PMID: 24148822
亞細胞定位：

Nucleus.
組織特異性：

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
數據庫鏈接：

HGNC: 13544

OMIM: 607268

KEGG: hsa:54108

STRING: 9606.ENSP00000220913

UniGene: Hs.279704