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  4. CEACAM16 Antibody, Biotin conjugated

CEACAM16 Antibody, Biotin conjugated

  • 中文名稱：
    CEACAM16兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA005158LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CEACAM16 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CEACAM16
  • 別名：
    CEACAM16 antibody; CEAL2Carcinoembryonic antigen-related cell adhesion molecule 16 antibody; Carcinoembryonic antigen-like 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 16 protein (323-414AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
  • 基因功能參考文獻：
    1. Results confirm that CEACAM6 promoted cell proliferation mediated by cyclin D1/CDK4. PMID: 26497080
    2. Data indicate that a heterozygous missense mutation, c.505G>A (p.G169R) in exon 3 of the CEACAM16 gene (carcinoembryonic antigen-related cell adhesion molecule 16) was identified in autosomal dominant nonsyndromic hearing loss family. PMID: 25589040
    3. CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane PMID: 22544735
    4. data identify CEACAM16 as an alpha-tectorin-interacting protein that concentrates at the point of attachment of the TM to the stereocilia and, when mutated, results in ADNSHL at the DFNA4 locus PMID: 21368133
  • 相關疾病：
    Deafness, autosomal dominant, 4B (DFNA4B)
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 數據庫鏈接：

    HGNC: 31948

    OMIM: 614591

    KEGG: hsa:388551

    STRING: 9606.ENSP00000385576

    UniGene: Hs.456381