CDKL2 Antibody

產(chǎn)品詳情

Uniprot No.：

Q92772
基因名：

CDKL2
別名：

CDKL2Cyclin-dependent kinase-like 2 antibody; EC 2.7.11.22 antibody; Protein kinase p56 KKIAMRE antibody; Serine/threonine-protein kinase KKIAMRE antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human KKIAMRE.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻(xiàn)：
1. Results showed that the methylation levels of CDKL2 were higher in hepatocellular carcinoma (HCC) cell lines and tissues but the mRNA expression levels decreased both in HCC tissues and cell lines. CDKL2 status seems to correlate with tumor size and may play an important role in hepatocarcinogenesis. PMID: 30292871
2. High CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression. PMID: 25333262
3. We hypothesized that LA might induce dissociation of p56(Lck) from CD4, thus leading to its downmodulation. PMID: 16631599
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
組織特異性：

Expressed in testis and kidney, and at lower level in brain and lung.
數(shù)據(jù)庫鏈接：

HGNC: 1782

OMIM: 603442

KEGG: hsa:8999

STRING: 9606.ENSP00000412365

UniGene: Hs.591698