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CDK5R2 Antibody

  • 中文名稱：
    CDK5R2兔多克隆抗體
  • 貨號：
    CSB-PA003663
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEc cells using p39 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CDK5R2
  • 別名：
    CD5R2_HUMAN antibody; CDK5 activator 2 antibody; Cdk5r2 antibody; Cyclin dependent kinase 5 activator 2 antibody; Cyclin dependent kinase 5 activator isoform p39i antibody; Cyclin dependent kinase 5 regulatory subunit 2 antibody; Cyclin-dependent kinase 5 activator 2 antibody; Cyclin-dependent kinase 5 regulatory subunit 2 antibody; NCK5AI antibody; Neuronal CDK5 activator isoform antibody; p39 antibody; P39I antibody; p39nck5ai antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human p39.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Activator of CDK5/TPKII.
  • 基因功能參考文獻：
    1. p39 is essential for recruiting scaffolding protein muskelin to stress fibers. PMID: 25128817
    2. Hepatocellular carcinoma patients with lower p39 expression had poorer overall survival rate than that with high expression. PMID: 20936377
    3. Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 to p29, which might contribute to deregulation of Cdk5 PMID: 11784720
    4. role of the CDK5 molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease PMID: 15917097
  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Cyclin-dependent kinase 5 activator family
  • 組織特異性：
    Brain and neuron specific.
  • 數據庫鏈接：

    HGNC: 1776

    OMIM: 603764

    KEGG: hsa:8941

    STRING: 9606.ENSP00000304250

    UniGene: Hs.158460