CCNL2 Antibody

產品詳情

Uniprot No.：

Q96S94
基因名：

CCNL2
別名：

CCNL2 antibody; SB138Cyclin-L2 antibody; Paneth cell-enhanced expression protein antibody
反應種屬：

Human,Mouse,Rat
免疫原：

Human CCNL2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.
基因功能參考文獻：
1. Therefore, cyclin L2-mediated control of SAMHD1 levels in macrophages supports HIV-1 replication. PMID: 25532805
2. CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. PMID: 24218572
3. characterize cyclin L2 as a highly mobile component of nuclear speckles and suggest that DYRK1A may regulate splicing by phosphorylation of cyclin L2 PMID: 14623875
4. represents a new member of the cyclin family, which might regulate the transcription and RNA processing of certain apoptosis-related factors PMID: 14684736
亞細胞定位：

Nucleus speckle. Nucleus, nucleoplasm.
蛋白家族：

Cyclin family, Cyclin L subfamily
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 20570

OMIM: 613482

KEGG: hsa:81669

STRING: 9606.ENSP00000383611

UniGene: Hs.515704