ASZ1 Antibody

產(chǎn)品詳情

Uniprot No.：

Q8WWH4
基因名：

ASZ1
別名：

ASZ1 antibody; ALP1 antibody; ANKL1 antibody; C7orf7 antibody; GASZAnkyrin repeat antibody; SAM and basic leucine zipper domain-containing protein 1 antibody; Ankyrin-like protein 1 antibody; Germ cell-specific ankyrin antibody; SAM and basic leucine zipper domain-containing protein antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human ASZ1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
基因功能參考文獻(xiàn)：
1. Data reveal a potential role of GASZ during embryonic germ cell development and provide a powerful in vitro system for dissecting the molecular pathways in early germ cell formation during embryogenesis. PMID: 23816659
亞細(xì)胞定位：

Cytoplasm.
組織特異性：

Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
數(shù)據(jù)庫鏈接：

HGNC: 1350

OMIM: 605797

KEGG: hsa:136991

STRING: 9606.ENSP00000284629

UniGene: Hs.352412