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ABCA5 Antibody

  • 中文名稱：
    ABCA5兔多克隆抗體
  • 貨號：
    CSB-PA845163LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA845163LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA845163LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ABCA5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ABCA5
  • 別名：
    ABC13 antibody; ABCA5 antibody; ABCA5_HUMAN antibody; ATP binding cassette sub family A (ABC1) member 5 antibody; ATP binding cassette A5 antibody; ATP binding cassette sub family A member 5 antibody; ATP-binding cassette sub-family A member 5 antibody; DKFZp451F117 antibody; DKFZp779N2435 antibody; EST90625 antibody; FLJ16381 antibody; KIAA1888 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ABCA5 Antibody (CSB-PA845163LA01HU)，的標記方式是Non-conjugated。對于ABCA5 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA845163LB01HU ABCA5 Antibody, HRP conjugated ELISA
    FITC CSB-PA845163LC01HU ABCA5 Antibody, FITC conjugated
    Biotin CSB-PA845163LD01HU ABCA5 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes.
  • 基因功能參考文獻：
    1. This report represents the first extensive expression and functional study of ABCA5 in the human brain and our data suggest a plausible function of ABCA5 in the brain as a cholesterol transporter associated with Abeta generation PMID: 25125465
    2. our findings support ABCA5 as a gene underlying the congenital generalized hypertrichosis terminalis phenotype and suggest a novel, previously unrecognized role for this gene in regulating hair growth. PMID: 24831815
    3. The expression of ABCA5 was significantly elevated in parkinson disease brains compared to age- and gender-matched control brains. PMID: 23939407
    4. The ABCB5 gene may be related to the properties of chemoresistance and aggressiveness of melanoma PMID: 20487690
    5. Cloning of ABCA5 and detection of a splice variant. PMID: 12504089
    6. ABCA5 may have a role in prostatic intraepithelial neoplasia PMID: 17289887
    7. There is a correlation of induction of ABCA5 and mRNA with differentiation of colonic neoplasms. PMID: 17541169

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  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell membrane.
  • 蛋白家族：
    ABC transporter superfamily, ABCA family
  • 組織特異性：
    Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta. Expressed in both the epithelial and mesenchymal compartments, present within the outer root sheath (ORS) of the hair follicle as well as dermal sheath. Expre
  • 數據庫鏈接：

    HGNC: 35

    OMIM: 612503

    KEGG: hsa:23461

    STRING: 9606.ENSP00000376443

    UniGene: Hs.731824