国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 單克隆抗體
  4. UBE2Z Monoclonal Antibody

UBE2Z Monoclonal Antibody

  • 中文名稱：
    UBE2Z Monoclonal Antibody
  • 貨號(hào)：
    CSB-MA105090
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of UBE2Z expression in HepG2 cells using UBE2Z antibody. Green, isotype control; red, UBE2Z.
    • Western blotting analysis using UBE2Z antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with UBE2Z antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
    • Western blotting analysis using UBE2Z antibody. UBE2Z expression in wild-type (WT) and UBE2Z shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with UBE2Z antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Mouse anti-Homo sapiens (Human) UBE2Z Monoclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    UBE2Z; Ubiquitin Conjugating Enzyme E2 Z; USE1; Uba6-Specific E2 Conjugating Enzyme 1; Ubiquitin-Conjugating Enzyme E2 Z; E2 Ubiquitin-Conjugating Enzyme Z; Ubiquitin Carrier Protein Z; Ubiquitin-Protein Ligase Z; UBA6-Specific Enzyme E2; FLJ13855; Ubiquitin-Conjugating Enzyme E2Z; Ubiquitin Conjugating Enzyme E2Z; EC 2.3.2.23; EC 6.3.2.19; HOYS7; Use1
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human UBE2Z protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG2b
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    21A9
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:400-1:2000
    FC 1:100-1:1000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.
  • 基因功能參考文獻(xiàn)：
    1. The SNP rs46522 in UBE2Z gene is associated with the risk of coronary Artery disease in the individuals of Chinese Han descent with type 2 diabetes and is of synergistic effect with Body mass index. PMID: 28840129
    2. we found that USE1 proteins were frequently overexpressed in human lung cancer. Furthermore, overexpression of USE1 promoted in vivo and in vitro proliferation, migration, and invasion. PMID: 28376205
    3. Association of UBE2Z single nucleotide polymorphism rs46522 with the susceptibility to coronary artery disease in an Iranian population. PMID: 26602883
    4. UBE2Z was widely expressed in human tissues and is located on chromosome 17q21. PMID: 17160626
    5. In tissue culture cells, Uba6 is required for charging a previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is required for charging the cell-cycle E2s Cdc34A and Cdc34B PMID: 17597759

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 組織特異性：
    Widely expressed. Highly in placenta, pancreas, spleen and testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 25847

    OMIM: 611362

    KEGG: hsa:65264

    STRING: 9606.ENSP00000354201

    UniGene: Hs.514297