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TRIM47 Monoclonal Antibody

  • 中文名稱：
    TRIM47 Monoclonal Antibody
  • 貨號：
    CSB-MA150588
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of TRIM47 expression in H9c2 cells using TRIM47 antibody. Green, isotype control; red, TRIM47.
    • Western blotting analysis using TRIM47 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with TRIM47 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
    • Western blotting analysis using TRIM47 antibody. TRIM47 expression in wild-type (WT) and TRIM47 knockdown (KD) HeLa cells with 30 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with TRIM47 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產品詳情

  • 產品名稱：
    Mouse anti-Homo sapiens (Human) TRIM47 Monoclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIM47
  • 別名：
    TRIM47; Tripartite Motif Containing 47; RNF100; GOA; Gene Overexpressed In Astrocytoma Protein; Tripartite Motif-Containing Protein 47; E3 Ubiquitin-Protein Ligase TRIM47; RING Finger Protein 100; Tripartite Motif-Containing 47; EC 2.3.2.27
  • 宿主：
    Mouse
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human TRIM47 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    24E3
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:200-1:1000
    FC 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD.
  • 基因功能參考文獻：
    1. Study shows that protein and gene expression level of TRIM47 are up-regulated in prostate neoplasm. PMID: 26873435
    2. High TRIM47 expression is associated with non-small cell lung carcinoma. PMID: 28186994
    3. These results suggest that rs1055129 in TRIM47 is not associated with leukoaraiosis (LA) risk in the Chinese population. However, the association of rs1055129 (TRIM47) with LA before Bonferroni correction and Sidak correction is worth highlighting. PMID: 27583843
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.
  • 數據庫鏈接：

    HGNC: 19020

    OMIM: 611041

    KEGG: hsa:91107

    STRING: 9606.ENSP00000254816

    UniGene: Hs.293660