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REEP2 Monoclonal Antibody

  • 中文名稱：
    REEP2 Monoclonal Antibody
  • 貨號：
    CSB-MA923620
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of REEP2 expression in HeLa cells using REEP2 antibody. Green, isotype control; red, REEP2.
    • Western blotting analysis using REEP2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with REEP2 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Mouse anti-Homo sapiens (Human) REEP2 Monoclonal antibody
  • Uniprot No.：
  • 基因名：
    REEP2
  • 別名：
    REEP2; Receptor Accessory Protein 2; SGC32445; C5orf19; SPG72; Yip2d; Receptor Expression-Enhancing Protein 2; Chromosome 5 Open Reading Frame 19; SPG72A; SPG72B
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human REEP2 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG2a
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    20C11
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2500
    FC 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors.
  • 基因功能參考文獻(xiàn)：
    1. Expression of the REEP1/REEP2 subfamily appears to be restricted to neuronal and neuronal-like exocytotic tissues, consistent with neuronally restricted symptoms of REEP1 genetic disorders. PMID: 24355597
    2. We have identified mutations in REEP2 in two families with relatively pure, early-onset hereditary spastic paraplegia, one with autosomal-dominant and the other with autosomal-recessive transmission. PMID: 24388663
    3. In mouse, Reep2 enhances sweet receptor function by a different mechanism than Reep1 uses to enhance olfactory receptor function. PMID: 20943918
  • 相關(guān)疾病：
    Spastic paraplegia 72 (SPG72)
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    DP1 family
  • 組織特異性：
    Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas. Expressed in circumvallate papillae.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17975

    OMIM: 609347

    KEGG: hsa:51308

    STRING: 9606.ENSP00000254901

    UniGene: Hs.416090