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NDUFB10 Monoclonal Antibody

  • 中文名稱：
    NDUFB10 Monoclonal Antibody
  • 貨號：
    CSB-MA827947
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of NDUFB10 expression in HepG2 cells using NDUFB10 antibody. Green, isotype control; red, NDUFB10.
    • Immunocytochemical staining of HepG2 cells with NDUFB10 antibody. Nuclei were stained blue with DAPI; NDUFB10 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 μm.
    • Western blotting analysis using NDUFB10 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with NDUFB10 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產品詳情

  • 產品名稱：
    Mouse anti-Homo sapiens (Human) NDUFB10 Monoclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NDUFB10; NADH:Ubiquinone Oxidoreductase Subunit B10; PDSW; NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 10, 22kDa; NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 10; NADH-Ubiquinone Oxidoreductase PDSW Subunit; Complex I PDSW Subunit; Complex I-PDSW; CI-PDSW; NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 10 (22kD, PDSW); NADH Ubiquinone Oxidoreductase PDSW Subunit (RH 16p13.3); MC1DN35
  • 宿主：
    Mouse
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human NDUFB10 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    4B6
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:400-1:2000
    FC 1:100-1:1000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
  • 基因功能參考文獻：
    1. findings indicate that mutations in NDUFB10 are a novel cause of complex I deficiency associated with a late stage assembly defect and emphasize the role of intermembrane space proteins for the efficient assembly of complex I. PMID: 28040730
    2. Src kinase inhibition led to a decrease in mitochondrial respiration via a specific decrease in complex I activities which is associated with a lower phosphorylation of the complex I subunit NDUFB10. PMID: 22321370
  • 亞細胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Complex I NDUFB10 subunit family
  • 數據庫鏈接：

    HGNC: 7696

    OMIM: 603843

    KEGG: hsa:4716

    STRING: 9606.ENSP00000268668

    UniGene: Hs.513266



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