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MRPS27 Monoclonal Antibody

  • 中文名稱：
    MRPS27 Monoclonal Antibody
  • 貨號：
    CSB-MA908537
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of MRPS27 expression in HT-1080 cells using MRPS27 antibody. Green, isotype control; red, MRPS27.
    • Western blotting analysis using anti-MRPS27 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-MRPS27 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產品詳情

  • 產品名稱：
    Mouse anti-Homo sapiens (Human) MRPS27 Monoclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    MRPS27; Mitochondrial Ribosomal Protein S27; KIAA0264; MS27; 28S Ribosomal Protein S27, Mitochondrial; Small Ribosomal Subunit Protein MS27; MRP-S27; S27mt?; Mitochondrial Small Ribosomal Subunit Protein MS27; Mitochondrial 28S Ribosomal Protein S27
  • 宿主：
    Mouse
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human MRPS27 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG2b
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    3C8
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2500
    FC 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth.
  • 基因功能參考文獻：
    1. we verified for the first time that mitochondrial ribosomal protein S23 expression was upregulated in hepatocellular carcinoma. High mitochondrial ribosomal protein S23 levels can predict poor clinical outcomes in hepatocellular carcinoma, and this protein plays a key role in tumor proliferation. Therefore, mitochondrial ribosomal protein S23 may be a potential therapeutic target for hepatocellular carcinoma. PMID: 28714366
    2. MRPS27 is required for mitochondrial protein synthesis PMID: 22841715
  • 亞細胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mS27 family
  • 組織特異性：
    Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level). Ubiquitous.
  • 數據庫鏈接：

    HGNC: 14512

    OMIM: 611989

    KEGG: hsa:23107

    STRING: 9606.ENSP00000261413

    UniGene: Hs.482491