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MMAE&MMAF Monoclonal Antibody

  • 中文名稱:
    MMAE&MMAF鼠單克隆抗體
  • 貨號:
    CSB-MA903890I1m
  • 規格:
    ¥3000
  • 圖片:
    • MMAE&MMAF antibody on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.
    • The Binding Activity of Disitamab vedotin (Synonyms: RC48) with Anti-MMAE&MMAF antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) at 2 μg/mL can bind Anti-MMAE antibody, the EC50 is 1.908 to 2.492 ng/mL.
    • The Binding Activity of Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC50 is 1.927 to 3.280 ng/mL.
    • The Binding Activity of Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC50 is 1.908 to 2.492 ng/mL and 1.927 to 3.280 ng/mL, respectively.
  • 其他:

產品詳情

  • 產品描述:
    CUSABIO針對MMAE(Monomethyl auristatin E,別名SGD-1010、Vedotin)和MMAF(Monomethylauristatin F)的單克隆抗體,僅供科研使用。該抗體經Protein G純化,純度大于95%,亞型為小鼠IgG2b。其特異性識別MMAE-BSA偶聯物,適用于ELISA檢測等免疫學實驗。 產品配方含50%甘油、0.01M PBS(pH 7.4),并添加0.03% Proclin 300作為防腐劑,以確保儲存穩定性。收到產品后,請立即存放于-20°C或-80°C環境,避免反復凍融,以免影響抗體活性。 MMAE和MMAF是一類合成的微管蛋白抑制劑,常作為抗體藥物偶聯物(ADC)的細胞毒性載荷,在抗腫瘤研究中具有重要應用。本抗體可用于檢測生物樣品中MMAE的存在與含量,為ADC藥物的研發、藥效評估及相關機制研究提供可靠的免疫學檢測工具。 注:本產品僅用于實驗室科研領域,不可用于臨床診斷、治療或其他非科研用途。產品發貨周期為2-3個工作日,確保及時滿足實驗需求。
  • 基因名:
    MMAE; MMAF
  • 別名:
    MMAE, Monomethyl auristatin E, SGD-1010, Vedotin; MMAF, Monomethylauristatin F
  • 宿主:
    Mouse
  • 反應種屬:
    Homo sapiens (Human)
  • 免疫原:
    MMAE-BSA
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    IgG2b
  • 純化方式:
    >95%, Protein G purified
  • 克隆號:
    25G12B5
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價



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