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GRHPR Monoclonal Antibody

  • 中文名稱：
    GRHPR Monoclonal Antibody
  • 貨號：
    CSB-MA149537
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Western blotting analysis using GRHPR antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GRHPR antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Mouse anti-Homo sapiens (Human) GRHPR Monoclonal antibody
  • Uniprot No.：
  • 基因名：
    GRHPR
  • 別名：
    GRHPR; Glyoxylate And Hydroxypyruvate Reductase; Glyoxylate Reductase/Hydroxypyruvate Reductase; GLXR; PH2; Glyoxylate Reductase And Hydroxypyruvate Reductase; Epididymis Secretory Sperm Binding Protein; Primary Hyperoxaluria Type 2; Glycerate-2-Dehydrogenase; EC 1.1.1.79; EC 1.1.1.81; GLYD
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human GRHPR protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    21A9
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
  • 基因功能參考文獻：
    1. GRHPR was genotyped in Japanese patients with PH2 and all GRHPR mutations described to date were reviewed in terms of geographic and ethnic association PMID: 24116921
    2. Our findings suggest that the GRHPR defect in noncancerous tissues may represent an independent predictor of poor survival for hepatocellular carcinoma patients after curative resection PMID: 23486161
    3. GRHPR directly interacts with SVCT1. PMID: 23599041
    4. substrate specificity of human glyoxylate reductase PMID: 16756993
    5. the GRHPR gene may have a role in primary hyperoxaluria type 2 in a Japanese patient [case report] PMID: 17510093

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  • 相關(guān)疾病：
    Hyperoxaluria primary 2 (HP2)
  • 蛋白家族：
    D-isomer specific 2-hydroxyacid dehydrogenase family
  • 組織特異性：
    Ubiquitous. Most abundantly expressed in the liver.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4570

    OMIM: 260000

    KEGG: hsa:9380

    STRING: 9606.ENSP00000313432

    UniGene: Hs.155742