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GPD2 Monoclonal Antibody

  • 中文名稱：
    GPD2 Monoclonal Antibody
  • 貨號：
    CSB-MA570126
  • 規格：
    ￥1320
  • 圖片：
    • Western blotting analysis using GPD2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GPD2 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
    • Western blotting analysis using GPD2 antibody. GPD2 expression in wild-type (WT) and GPD2 shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with GPD2 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產品詳情

  • 產品名稱：
    Mouse anti-Homo sapiens (Human) GPD2 Monoclonal antibody
  • Uniprot No.：
  • 基因名：
    GPD2
  • 別名：
    GPD2; Glycerol-3-Phosphate Dehydrogenase 2; Glycerol-3-Phosphate Dehydrogenase 2 (Mitochondrial); Glycerol-3-Phosphate Dehydrogenase, Mitochondrial; EC 1.1.5.3; GPDH-M; GPD-M; MtGPD; MGDH; Mitohondrial Glycerophosphate Dehydrogenase Gene; Mitochondrial Glycerophosphate Dehydrogenase; Mitohondrial Glycerophosphate Dehydrogenase; Testicular Tissue Protein Li 76; MGPDH; GDH2; GPDM
  • 宿主：
    Mouse
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human GPD2 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    11G6
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:400-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.
  • 基因功能參考文獻：
    1. testis-specific promoter of mitochondrial GPDH PMID: 15456763
    2. Overall, these data demonstrate that mGPDH is involved in maintaining a high rate of glycolysis and is an important site of electron leakage leading to ROS production in prostate cancer cells. PMID: 15967408
    3. the up-regulation of mGPDH, due to a highly glycolytic environment, contributes to the overall increase in ROS generation and may result in the progression of prostate cancer PMID: 17886033
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    FAD-dependent glycerol-3-phosphate dehydrogenase family
  • 數據庫鏈接：

    HGNC: 4456

    OMIM: 138430

    KEGG: hsa:2820

    STRING: 9606.ENSP00000308610

    UniGene: Hs.512382