EFHD1 Monoclonal Antibody
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中文名稱(chēng)：EFHD1鼠單克隆抗體
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貨號(hào)：CSB-MA000243
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規(guī)格：￥1090
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圖片：
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IF analysis of Hela with antibody (Left) and DAPI (Right) diluted at 1:100. -
Western blot analysis of 1) Mouse spleen tissue, 2) Rat spleen tissue, diluted at 1:3000.
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：EFHD1單克隆抗體（CUSABIO貨號(hào)：CSB-MA000243）是針對(duì)鈣結(jié)合蛋白EFHD1開(kāi)發(fā)的高特異性科研試劑，該靶點(diǎn)通過(guò)EF-hand結(jié)構(gòu)域參與細(xì)胞內(nèi)鈣信號(hào)轉(zhuǎn)導(dǎo)，在神經(jīng)分化過(guò)程中呈現(xiàn)顯著表達(dá)上調(diào)特征，對(duì)腦發(fā)育及腫瘤微環(huán)境調(diào)控具有重要研究?jī)r(jià)值。本產(chǎn)品經(jīng)嚴(yán)格驗(yàn)證適用于人、小鼠、大鼠三物種樣本，支持ELISA、Western Blot、免疫組化及免疫熒光四大實(shí)驗(yàn)平臺(tái)，可為神經(jīng)生物學(xué)、腫瘤轉(zhuǎn)移機(jī)制等基礎(chǔ)研究提供可靠工具。抗體采用100μL標(biāo)準(zhǔn)規(guī)格封裝，有效期為12個(gè)月，經(jīng)多次質(zhì)控確保批次穩(wěn)定性，滿足科研場(chǎng)景下蛋白定位、定量分析及組織切片檢測(cè)等多元化需求，特別適用于探索EFHD1在神經(jīng)發(fā)育調(diào)控和腫瘤微環(huán)境中的分子作用機(jī)制。
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Uniprot No.：
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基因名：EFHD1
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別名：4931430I01Rik antibody; AI452351 antibody; DKFZp781H0842; antibody; EF hand domain containing 1 antibody; EF hand domain family; member D1 antibody; EF-hand domain-containing protein 1 antibody; EF-hand domain-containing protein D1 antibody; EFHD1 antibody; EFHD1_HUMAN antibody; FLJ13612 antibody; MGC103094 antibody; Mitocalcin antibody; MST133 antibody; MSTP133 antibody; PP3051 antibody; RGD1559565 antibody; Swiprosin 2 antibody; Swiprosin-2 antibody; SWS2 antibody
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宿主：Mouse
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Synthetic Peptide
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免疫原種屬：H, M, R
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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克隆號(hào)：7B5
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC,IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:50-1:500 IF 1:50-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情
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功能：Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation.
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基因功能參考文獻(xiàn)：
- EFHD1 functions as a novel mitochondrial Ca(2+) sensor underlying Ca(2+)-dependent activation of mitoflashes PMID: 26975899
- detection of methylation of PPP1R3C alone or in combination with EFHD1 in plasma DNA showed high sensitivity and specificity in CRC detection, and may be useful detection method for CRC, especially for early-stage CRCs. PMID: 24861485
- Cloning of novel mouse genes associated with neuronal function, including Efhd1. PMID: 12270117
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亞細(xì)胞定位：Mitochondrion inner membrane.
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數(shù)據(jù)庫(kù)鏈接：
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