DDB1單克隆抗體（CUSABIO貨號(hào)：CSB-MA202984）是針對(duì)DNA損傷結(jié)合蛋白1（DDB1）研發(fā)的高特異性科研試劑，適用于人、小鼠、大鼠及猴等多物種樣本的檢測(cè)。DDB1作為核苷酸切除修復(fù)通路的核心因子，通過與DDB2形成復(fù)合物識(shí)別紫外線誘導(dǎo)的DNA損傷，同時(shí)在CUL4A泛素連接酶復(fù)合體中參與細(xì)胞周期調(diào)控及腫瘤抑制等重要生物學(xué)過程，其功能異常與多種癌癥發(fā)生及細(xì)胞衰老密切相關(guān)。本產(chǎn)品經(jīng)ELISA和Western Blot（WB）雙重方法學(xué)驗(yàn)證，抗體效價(jià)穩(wěn)定，可精準(zhǔn)識(shí)別天然及變性狀態(tài)下的DDB1蛋白，適用于DNA損傷修復(fù)機(jī)制研究、癌癥相關(guān)信號(hào)通路分析以及細(xì)胞周期調(diào)控實(shí)驗(yàn)等科研場(chǎng)景。該單克隆抗體具有高度批間一致性，為研究者提供可靠的實(shí)驗(yàn)數(shù)據(jù)支持，特別適用于基因組穩(wěn)定性研究、腫瘤分子生物學(xué)實(shí)驗(yàn)及抗衰老相關(guān)機(jī)制探索，是研究DNA損傷應(yīng)答系統(tǒng)及泛素-蛋白酶體通路的重要工具。

Damage specific DNA binding protein 1; Damage-specific DNA-binding protein 1; DDB 1; DDB p127 subunit; Ddb1; DDB1_HUMAN; DDBa; DNA damage binding protein 1; DNA damage-binding protein 1; DNA damage-binding protein a; HBV X-associated protein 1;

Mouse

Human,Mouse,Rat,Monkey

Purified recombinant Human DDB1 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2b

27F12

It differs from different batches. Please contact us to confirm it.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

ELISA,WB

Application	Recommended Dilution
WB	1:500-1:5000

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.