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CSNK1E Monoclonal Antibody

  • 中文名稱：
    CSNK1E Monoclonal Antibody
  • 貨號：
    CSB-MA779862
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of Casein kinase 1 epsilon expression in HT-1080 cells using Casein kinase 1 epsilon antibody. Green, isotype control; red, Casein kinase 1 epsilon.
    • Immunocytochemical staining of HepG2 cells with Casein kinase 1 epsilon antibody. Nuclei were stained blue with DAPI; Casein kinase 1 epsilon was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
    • Western blotting analysis using casein kinase 1 epsilon antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with casein kinase 1 epsilon antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產品詳情

  • 產品名稱：
    Mouse anti-Homo sapiens (Human) CSNK1E Monoclonal antibody
  • Uniprot No.：
  • 基因名：
    CSNK1E
  • 別名：
    CSNK1E; Casein Kinase 1 Epsilon; CKIepsilon; HCKIE; CKIE; Casein Kinase I Isoform Epsilon; EC 2.7.11.1; Casein Kinase 1, Epsilon; CKI-Epsilon; EC 2.7.11; CKIe
  • 宿主：
    Mouse
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human CSNK1E protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    16E10
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:2500
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
  • 基因功能參考文獻：
    1. CKI-epsilon is a potent TDP-43 kinase in vivo and in vitro. PMID: 24105464
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
  • 組織特異性：
    Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
  • 數據庫鏈接：

    HGNC: 2453

    OMIM: 600863

    KEGG: hsa:102800317

    STRING: 9606.ENSP00000352929

    UniGene: Hs.474833