国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Rat Keratinocyte Growth Factor,KGF ELISA Kit

Rat Keratinocyte Growth Factor,KGF ELISA Kit

  • 中文名稱：
    大鼠角化細胞生長因子(KGF)酶聯免疫試劑盒
  • 貨號：
    CSB-E12905r
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 促銷：
  • 其他：

產品詳情

  • 產品描述：
    大鼠角化細胞生長因子(KGF)酶聯免疫試劑盒（CSB-E12905r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿樣本中的FGF7含量。FGF7即成纖維細胞生長因子 7，屬于FGF家族。它在胚胎發育、組織修復等過程發揮重要作用，可促進上皮細胞的增殖、遷移等。其研究機制主要圍繞與受體結合激活下游信號通路，在腫瘤、皮膚疾病等領域是潛在治療靶點。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL，適用于皮膚損傷修復機制、上皮細胞再生調控、藥物干預效果評估等基礎研究領域，為探索KGF在組織穩態維持及疾病模型中的作用提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Fgf7 ELISA Kit; Fgf-7 ELISA Kit; KgfFibroblast growth factor 7 ELISA Kit; FGF-7 ELISA Kit; Heparin-binding growth factor 7 ELISA Kit; HBGF-7 ELISA Kit; Keratinocyte growth factor ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Rattus norvegicus (Rat)
  • 樣本類型：
    serum, plasma
  • 檢測范圍：
    31.25 pg/mL-2000 pg/mL
  • 靈敏度：
    7.81 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of rat KGF in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %86
    Range %81-95
    1:2Average %95
    Range %89-101
    1:4Average %92
    Range %87-96
    1:8Average %86
    Range %80-93
  • 回收率：
    The recovery of rat KGF spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 10094-105
    EDTA plasma (n=4)9589-99
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    20002.730 2.775 2.753 2.621
    10002.226 2.403 2.315 2.183
    5001.500 1.610 1.555 1.423
    2500.837 0.890 0.864 0.732
    1250.428 0.432 0.430 0.298
    62.50.221 0.235 0.228 0.096
    31.20.167 0.158 0.163 0.031
    00.130 0.133 0.132 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
  • 基因功能參考文獻：
    1. The findings of the present study indicated that KGF, CTGF and TGF-beta have biological roles in progression of CsA- and PNT- induced GO. KGF plays a greater role in CsA- induced GO than in PNT- induced GO. Meanwhile, CTGF and TGF-beta play a role in PNT- induced GO greater than in CsA- induced GO. PMID: 26894526
    2. These data demonstrate that administration of MSCs to the inflammation-insulted AT-II cells may ameliorate the impairments through a KGF-dependent PI3K/AKT/mTOR signaling pathway. PMID: 27035760
    3. The primary role of both KGF1 and FGF2 appeared to be in the proliferation and migration of keratinocytes PMID: 21136143
    4. KGF may have a role in ameliorating radiation-induced pulmonary injury in rats PMID: 21436609
    5. KGF promotes preadipocyte proliferation by an autocrine mechanism that involves activation of the PI3K/Akt signaling pathway PMID: 20069574
    6. Keratinocyte growth factor may promote alveolar epithelial repair through several mechanisms involved in cell migration PMID: 12581741
    7. Decreased gene expression of FGF-7 in the rat hypoplastic lung suggests that pulmonary hypoplasia in nitrofen-induced congenital diaphragmatic hernia rat may be caused by reduced synthesis of FGF-7 during lung morphogenesis. PMID: 12861530
    8. KGF stimulates lipogenesis in alveolar type II cells by a coordinated expression of lipogenic enzymes and transport proteins regulated by C/EBP isoforms and SREBP-1c PMID: 12865412
    9. stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 and 3 PMID: 14506240
    10. Exogenous administered KGF cDNA causes increases in IGF-I, IGF-BP3, FGF, and collagen IV and decreases TGF-beta concentration. KGF gene transfer accelerates wound healing without causing an increase in collagen I or III. PMID: 17292422
    11. KGF improves alterations of lung permeability and bronchial epithelium in allergic rats PMID: 17392324
    12. retention of the AT2 cell phenotype by KGF involves c-Jun and suggest that activation of c-Jun kinase may be an important determinant of maintenance of AT2 cell phenotype PMID: 17872496
    13. FGF-7, most likely through its effect on the vascular bed, is required for normal early postnatal alveolar formation from secondary crests. PMID: 18091341
    14. the effects of KGF on duct cell proliferation are mediated by the MEK-ERK1/2 pathway, while the KGF-induced cell differentiation is mediated by the PI3K/AKT pathway PMID: 19266047

    顯示更多

    收起更多

  • 蛋白家族：
    Heparin-binding growth factors family
  • 數據庫鏈接：


主站蜘蛛池模板： 古交市| 招远市| 苗栗市| 凉城县| 扶风县| 旅游| 日照市| 和静县| 理塘县| 青海省| 英山县| 青州市| 恭城| 驻马店市| 庄河市| 潮安县| 荣昌县| 南江县| 南靖县| 林周县| 永泰县| 武平县| 云和县| 介休市| 台北市| 大石桥市| 西丰县| 德江县| 六枝特区| 沐川县| 外汇| 墨竹工卡县| 澄江县| 大兴区| 远安县| 石台县| 金川县| 广宁县| 汪清县| 雅安市| 南汇区|